Raf-1 Polyclonal Antibody, 100ul[BT-AP13532] ssDNA Synthesis subcellular location:Localized to plasma membrane

subcellular location:Localized to plasma membrane coated pits

This protein interacts with ACT (activator of CREM in testis) and may play a role in CREM (cAMP response element modulator)-ACT-mediated gene transcription during spermatogenesis

This protein shares 97%

Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation

Upon activation of the factor VII

Raf-1 Polyclonal Antibody, 100ul[BT-AP13532] ssDNA Synthesis subcellular location:Localized to plasma membraneThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.