CD57 Polyclonal Antibody, 50ul[BT-AP02190] PCR Series This protein binds to the

This protein binds to the SH3 domains of GRB2| an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras)| via its C-terminal proline-rich sequences| and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2

It is used prior to hematopoietic transplantation for peripheral blood stem cell mobilization and reduction of incidence| duration| and/or severity of chemotherapy induced cytopenias

They form a three-tiered signaling module composed of MAPKKKs

which is involved in large ribosomal subunit biogenesis

Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators

CD57 Polyclonal Antibody, 50ul[BT-AP02190] PCR Series This protein binds to theCPN2 (Carboxypeptidase N Subunit 2) is a Protein Coding gene. GO annotations related to this gene include enzyme regulator activity. An important paralog of this gene is LRRTM2. he 83 kDa subunit binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation. Under some circumstances it may be an allosteric modifier of the catalytic subunit.