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COL12A1 Polyclonal Antibody, 20ul Contamination Detection & Removal The mouse protein has been

SKU: 84860109339

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COL12A1 Polyclonal Antibody, 20ul Contamination Detection & Removal The mouse protein has beenThis gene encodes the alpha chain of type XII collagen, a member of the FACIT (fibril associated collagens with interrupted triple helices) collagen family. Type XII collagen is a homotrimer found in association with type I collagen, an association that is thought to modify the interactions between collagen I fibrils and the surrounding matrix. Alternatively spliced transcript variants encoding different isoforms have been identified.

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Description

The mouse protein has been shown to be capable of binding to heparin

An important paralog of this gene is HCAR3

Members of this family contain TFA domains and may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner

The 27 kDa form has no activity while the 22/25 kDa form can act as activator for collagenase

and functions as an important regulator of multiple signaling pathways in hematopoietic cells

COL12A1 Polyclonal Antibody, 20ul Contamination Detection & Removal The mouse protein has beenThis gene encodes the alpha chain of type XII collagen, a member of the FACIT (fibril associated collagens with interrupted triple helices) collagen family. Type XII collagen is a homotrimer found in association with type I collagen, an association that is thought to modify the interactions between collagen I fibrils and the surrounding matrix. Alternatively spliced transcript variants encoding different isoforms have been identified.

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