MAGA3 Polyclonal Antibody, 50ul Gene Synthesis Mutations affecting CD40 are the

Mutations affecting CD40 are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3)

the 5' end of C1R was annotated on NT_009714

This gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons

The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0)

the peptidase family S1

MAGA3 Polyclonal Antibody, 50ul Gene Synthesis Mutations affecting CD40 are theThis gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some