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SPAK(Phospho Ser323) Polyclonal Antibody, 50ul 3D Culture Assuming that human lipophilins are

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SPAK(Phospho Ser323) Polyclonal Antibody, 50ul 3D Culture Assuming that human lipophilins areThis gene encodes a serine threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation chloride coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the

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Description

Assuming that human lipophilins are the functional counterparts of prostatein| they may be transcriptionally regulated by steroid hormones| with the ability to bind androgens| other steroids and possibly bind and concentrate estramustine| a chemotherapeutic agent widely used for prostate cancer

Mutations in this gene cause autosomal dominant severe congenital neutropenia

The active form of the protein is found extracellularly as a homodimer

TFE3 (transcription factor binding to IGHM enhancer 3) encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes

It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits

SPAK(Phospho Ser323) Polyclonal Antibody, 50ul 3D Culture Assuming that human lipophilins areThis gene encodes a serine threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation chloride coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the

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