FKB1A Polyclonal Antibody, 100ul Immunology Alternative splicing of KRT13 results

Alternative splicing of KRT13 results in multiple transcript variants

The encoded protein is highly similar to the largest subunit of the Drosophila NURF (nucleosome remodeling factor) complex

This gene shares its 5' exon with the overlapping gene

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The encoded protein is involved in several cellular processes| including autophagic vesicle formation| mitochondrial quality control after oxidative damage| negative regulation of the innate antiviral immune response| lymphocyte development and proliferation| MHC II antigen presentation| adipocyte differentiation| and apoptosis

FKB1A Polyclonal Antibody, 100ul Immunology Alternative splicing of KRT13 resultsThe protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF beta receptor. It also interacts with multiple intracellular calcium