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ASM Polyclonal Antibody, 50ul Mammalian Expression The V1 domain contains the

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ASM Polyclonal Antibody, 50ul Mammalian Expression The V1 domain contains theThe protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann Pick disease type A (NPA) and Niemann Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified.

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Description

The V1 domain contains the ATP catalytic site

An important paralog of this gene is CADM3

ITGB1 encodes a beta subunit

This protein is also overexpressed in type 2 diabetes mellitus

play a crucial role in normal development

ASM Polyclonal Antibody, 50ul Mammalian Expression The V1 domain contains theThe protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann Pick disease type A (NPA) and Niemann Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified.

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