GRK2(Phospho-Tyr86) Polyclonal Antibody, 50ul Immuno Plates The laminins are a family

The laminins are a family of extracellular matrix glycoproteins that have a heterotrimeric structure consisting of an alpha

Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity

The integrin subunit beta 2 plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency

deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium

May be involved in the control of initiation of DNA replication through its interaction with NAKAP95

GRK2(Phospho-Tyr86) Polyclonal Antibody, 50ul Immuno Plates The laminins are a familyThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.