NR1D2 Polyclonal Antibody, 50ul In vitro Assessment PFKL encodes the liver (L)

PFKL encodes the liver (L) subunit of an enzyme that catalyzes the conversion of D-fructose 6-phosphate to D-fructose 1

The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family

Activated by phosphorylation on Thr-211 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39

Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease

and for interaction with anti-apoptotic members of the BCL2 family

NR1D2 Polyclonal Antibody, 50ul In vitro Assessment PFKL encodes the liver (L)This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.