PCNA Monoclonal Antibody(12D10), 100ul Diagnostic Probes & Oligos Shd (SH2 domain-containing adapter protein
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PCNA Monoclonal Antibody(12D10), 100ul Diagnostic Probes & Oligos Shd (SH2 domain-containing adapter proteinThe protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6 dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have
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