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FTO Polyclonal Antibody, 50ul Biomatrix This protein deubiquitinates target proteins

SKU: 87361644009

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FTO Polyclonal Antibody, 50ul Biomatrix This protein deubiquitinates target proteinsFTO is a nuclear protein of the AlkB related non haem iron and 2 oxoglutarate dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

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Description

This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling)

three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats

This gene encodes an NADPH sensor protein that preferentially binds to NADPH

The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue

motility or function

FTO Polyclonal Antibody, 50ul Biomatrix This protein deubiquitinates target proteinsFTO is a nuclear protein of the AlkB related non haem iron and 2 oxoglutarate dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

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