WWOX Polyclonal Antibody, 50ul Recombinant Ab Production Caspases mediate cellular apoptosis through

Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates

Compatible with glass or plastic serological pipettes(0

a large family of receptors that have a similar structure characterized by 7 transmembrane domains

observation and manipulationof samples during collection and storage

The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER

WWOX Polyclonal Antibody, 50ul Recombinant Ab Production Caspases mediate cellular apoptosis throughWWOX (WW domain containing oxidoreductase) encodes a member of the short chain dehydrogenases reductases (SDR) protein family. WWOX spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of WWOX is also associated with autosomal recessive spinocerebellar ataxia