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Pepsin C Polyclonal Antibody, 100ul Gene Synthesis a peptidylglycine alpha-hydroxylating monooxygenase (PHM)

SKU: 88248273294

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USD141.00 USD163.00

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Pepsin C Polyclonal Antibody, 100ul Gene Synthesis a peptidylglycine alpha-hydroxylating monooxygenase (PHM)PGC (progastricsin) encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the

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Description

a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain

Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma

protection from oxidative stress at the mitochondria

Mutations in EIF2AK3 are associated with Wolcott-Rallison syndrome

Cockayne's syndrome

Pepsin C Polyclonal Antibody, 100ul Gene Synthesis a peptidylglycine alpha-hydroxylating monooxygenase (PHM)PGC (progastricsin) encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the

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