PLXB1 Polyclonal Antibody, 100ul Electrophoresis & Labeling Alterations in levels of the

Alterations in levels of the encoded protein may be associated with many diseases

Several alternatively spliced transcript variants of this gene have been described| but their biological validity has not been determined

The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit

Upon activation of the alternative pathway

It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development

PLXB1 Polyclonal Antibody, 100ul Electrophoresis & Labeling Alterations in levels of thedisease: Overexpressed and constitutively tyrosine phosphorylated in colon, liver, pancreas and gastric carcinoma cell lines. Overexpression increases MET activation and promotes invasive growth.,Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.,PTM: Phosphorylated on tyrosine residues by ERBB2 and MET upon SEMA4D binding.,PTM: