NF-1 Polyclonal Antibody, 100ul Mammalian Expression suggesting that it may be

suggesting that it may be a good candidate for the del(5q) tumor suppressor gene

Gene Ontology (GO) annotations related to this gene include chromatin binding and protein complex binding

The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts to the trans-Golgi network through endosomes where a second autocatalytic event takes place and the Catalytic activity is acquired

Intracellular calcium regulates the physical association between the alpha and beta subunits

Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease

NF-1 Polyclonal Antibody, 100ul Mammalian Expression suggesting that it may beNFIA encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene.