CD27 Polyclonal Antibody, 20ul Centrifuges The encoded protein is important

The encoded protein is important in hematopoiesis

has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation

It is predicted to have a cytoplasmic C-terminus| 13 transmembrane domains| and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus

The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substrates

The encoded protein is related to a plant protein that participates in ultraviolet B light-sensing during root morphogenesis

CD27 Polyclonal Antibody, 20ul Centrifuges The encoded protein is importantThe protein encoded by this gene is a member of the TNF receptor superfamily. This receptor is required for generation and long term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF kappaB and MAPK8 JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this