ErbB-3(Phospho Tyr1222) Polyclonal Antibody, 100ul Aspirating Pipets and in same transcriptional orientation

and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24

This gene is one of several chemokine genes clustered on the q-arm of chromosome 17

a putative transmembrane domain

Exhibits the transport characteristics of the nucleoside transport system cit or N2 subtype (N2/cit) (selective for pyrimidine nucleosides and adenosine)

It functions as a transcriptional co-activator of serum response factor (SRF) and modulates expression of cardiac and smooth muscle-specific SRF-target genes

ErbB-3(Phospho Tyr1222) Polyclonal Antibody, 100ul Aspirating Pipets and in same transcriptional orientationThis gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the