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PAR-4 Polyclonal Antibody, 100ul Live Cell Imaging TLEs are differentially expressed during

SKU: 89146163771

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PAR-4 Polyclonal Antibody, 100ul Live Cell Imaging TLEs are differentially expressed duringThis gene encodes a member of the protease activated receptor subfamily, part of the G protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Hypomethylation at this gene may be associated with lung cancer in human patients.

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Description

TLEs are differentially expressed during animal development and may have overlapping as well as distinct functions

Functions cooperatively with CDC42 and Rac to generate additional structures

This gene encodes the smallest subunit of dynactin| a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD

Upon activation by the cleavage of the activation peptide by thrombin and in the presence of calcium ion

a nuclear factor involved in apoptotic DNA fragmentation

PAR-4 Polyclonal Antibody, 100ul Live Cell Imaging TLEs are differentially expressed duringThis gene encodes a member of the protease activated receptor subfamily, part of the G protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Hypomethylation at this gene may be associated with lung cancer in human patients.

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