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p53(Phospho Ser37) Polyclonal Antibody, 100ul Peripheral Blood Separation Tube and following ER stress-induced proteolysis

SKU: 89290628730

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p53(Phospho Ser37) Polyclonal Antibody, 100ul Peripheral Blood Separation Tube and following ER stress-induced proteolysisThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

and following ER stress-induced proteolysis

PRKACA encodes one of the catalytic subunits of protein kinase A

spleen and in lower levels in skeletal muscle

This gene belongs to a small family of FXYD-domain containing regulators of Na+/K+ ATPases which share a 35-amino acid signature sequence domain| beginning with the sequence PFXYD| and containing 7 invariant and 6 highly conserved amino acids

This gene is located at the 5' end of the HOXD gene cluster on chromosome 2

p53(Phospho Ser37) Polyclonal Antibody, 100ul Peripheral Blood Separation Tube and following ER stress-induced proteolysisThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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