DFNA5 Polyclonal Antibody, 50ul Variant Libraries Mitochondrial DNA polymerase is heterotrimeric

Mitochondrial DNA polymerase is heterotrimeric

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The heavy chain V region is encoded by 1 each of 3 types of genes: V genes (see MIM 147070)| joining (J) genes (see MIM 147010)| and diversity (D) genes (see MIM 146910)

resulting in downregulation of cell activation

the ZIM2 and PEG3 genes do not share exons

DFNA5 Polyclonal Antibody, 50ul Variant Libraries Mitochondrial DNA polymerase is heterotrimericHearing impairment is a heterogeneous condition with over 40 loci described. Non syndromic hearing impairment protein 5 encoded by DFNA5 is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene.