RFC5 Polyclonal Antibody, 20ul In vitro Assessment Mutations in this gene have

Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy

and JAK2 pathways

CSNK1A1 phosphorylates CTNNB1 at Ser-45

Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene

and overexpression of both DRAK proteins in NIH/3T3 cells induces morphological changes associated with apoptosis

RFC5 Polyclonal Antibody, 20ul In vitro Assessment Mutations in this gene haveThe elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 36 kD subunit. This subunit can interact with the C terminal region of PCNA. It forms a core complex with the 38 and 40