KCNN2 (SK2) Polyclonal Antibody, 100ul Protein Expression Mutations in this gene have

Mutations in this gene have been associated with medulloblastomas

one of which encodes a high-mobility group protein

though a direct link to any disorder has yet to be demonstrated

The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors

a protein essential for cell cycle progression through the G2/M transition

KCNN2 (SK2) Polyclonal Antibody, 100ul Protein Expression Mutations in this gene haveAction potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by