Human Clip-Associating Protein 2, CLASP2 ELISA Kit , 96T Diagnostic Probes & Oligos There are alternatively spliced transcript

There are alternatively spliced transcript variants described for this gene but the full length nature is not known yet

Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly

A second copy of this gene within the centromeric copy of the duplication has been described in the literature

Mutations in this gene are associated with the X-linked lysosomal storage disease mucopolysaccharidosis type II| also known as Hunter syndrome

Transcriptional expression of this gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import

Human Clip-Associating Protein 2, CLASP2 ELISA Kit , 96T Diagnostic Probes & Oligos There are alternatively spliced transcriptMicrotubule plus end tracking protein that promotes the stabilization of dynamic microtubules (PubMed: 26003921). Involved in the nucleation of noncentrosomal microtubules originating from the trans Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching