Cardiotrophin-1 Polyclonal Antibody, 20ul[BT-AP01170] Cytokines This gene may have arose

This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1

and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction

ATG4D (autophagy related 4D cysteine peptidase) belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases

The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies

and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization

Cardiotrophin-1 Polyclonal Antibody, 20ul[BT-AP01170] Cytokines This gene may have aroseThe protein (cardiotrophin 1) encoded by CTF1 is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST gp130 receoptor. Two transcript variants encoding different isoforms have been found for CTF1.