IL-34 Rabbit Polyclonal Antibody, 50ul Variant Libraries CCRL2 encodes a chemokine receptor

CCRL2 encodes a chemokine receptor like protein (C-C motif chemokine receptor like 2)

together with SNAP25 (synaptosome-associated protein of 25 kDa)

Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes

This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain

This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1)| which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis

IL-34 Rabbit Polyclonal Antibody, 50ul Variant Libraries CCRL2 encodes a chemokine receptorInterleukin 34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony stimulating factor 1 receptor (CSF1R; MIM 164770) (Lin et al. 2008