CHD8 Polyclonal Antibody, 50ul Human Genome Knockout Libraries The gene encodes a member
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CHD8 Polyclonal Antibody, 50ul Human Genome Knockout Libraries The gene encodes a memberThis gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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