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CLN3 Polyclonal Antibody, 20ul Stepper A similar gene disrupted in

SKU: 9379819065

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CLN3 Polyclonal Antibody, 20ul Stepper A similar gene disrupted inThis gene encodes a protein that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs). Many alternatively spliced transcript variants have been found for this gene.

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Description

A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation

Contains 5 C2HC-type zinc fingers

ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein

Each copy of the gene also contains a 10

It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid

CLN3 Polyclonal Antibody, 20ul Stepper A similar gene disrupted inThis gene encodes a protein that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs). Many alternatively spliced transcript variants have been found for this gene.

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