CD264 Polyclonal Antibody, 100ul Liquid Storage Consumables POLR3D (RNA polymerase III subunit

POLR3D (RNA polymerase III subunit D) complements a temperature-sensitive mutant isolated from the BHK-21 Syrian hamster cell line

The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest| and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells

In the presence of nucleoside triphosphates and the small GTP binding protein Ran| the complex moves into the nuclear pore complex and the importin subunits dissociate

This gene belongs to the non-CT (non cancer/testis) subgroup of the melanoma-associated antigen (MAGE) superfamily

Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor

CD264 Polyclonal Antibody, 100ul Liquid Storage Consumables POLR3D (RNA polymerase III subunitThe protein encoded by TNFRSF10D (TNF receptor superfamily member 10d) is a member of the TNF receptor superfamily. This receptor contains an extracellular TRAIL binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL induced cell apoptosis.