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GPR139 Polyclonal Antibody, 100ul Adeno-associated Virus Packaging VCFS is phenotypically related to

SKU: 95290043446

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GPR139 Polyclonal Antibody, 100ul Adeno-associated Virus Packaging VCFS is phenotypically related toGPR139 encodes a member of the rhodopsin family of G protein coupled receptors. The G protein coupled receptor 139 is almost exclusively expressed in the central nervous system. L tryptophan and L phenylalanine may act as the physiologic ligands of the encoded protein. Alternative splicing results in multiple transcript variants.

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Description

VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions

Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB)

Forms a complex with NFKBIB and NF-kappa-B heterodimer (p50/NFKB1 and p65/RELA)

They are composed of one alpha and two beta subunits

AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors

GPR139 Polyclonal Antibody, 100ul Adeno-associated Virus Packaging VCFS is phenotypically related toGPR139 encodes a member of the rhodopsin family of G protein coupled receptors. The G protein coupled receptor 139 is almost exclusively expressed in the central nervous system. L tryptophan and L phenylalanine may act as the physiologic ligands of the encoded protein. Alternative splicing results in multiple transcript variants.

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