FoxN4 Polyclonal Antibody, 50ul Culture Tubes The MAD proteins compete for

The MAD proteins compete for MAX binding with MYC

A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers

It forms a core complex with the 38 and 40 kDa subunits

E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes

as well as in stabilization of I-kappa-B-alpha (NFKBIA

FoxN4 Polyclonal Antibody, 50ul Culture Tubes The MAD proteins compete forMembers of the winged helix forkhead family of transcription factors, such as FOXN4, are characterized by a 110 amino acid DNA binding domain that can fold into a variant of the helix turn helix motif consisting of 3 alpha helices flanked by 2 large loops or wings. These transcription factors are involved in a variety of biologic processes as key regulators in development and metabolism (Li et al. 2004 [PubMed 15363391]).