RASL2 Polyclonal Antibody, 100ul Site-directed Mutagenesis Contains 1 myosin head-like domain

Contains 1 myosin head-like domain

Phosphorylation of Ser-122 is strongly stimulated by hypoxia

The protein encoded by this gene is a calcyclin binding protein

Integrally molded

The enzyme is a tetramer (relative molecular weight approximately 440

RASL2 Polyclonal Antibody, 100ul Site-directed Mutagenesis Contains 1 myosin head-like domainThis gene encodes a member of the GAP1 family of GTPase activating proteins that suppresses the Ras mitogen activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP bound state to the inactive GDP bound state and no longer activates downstream