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HLA Class I Polyclonal Antibody, 100ul[BT-AP10062] Thermo Mix The coding region of this

SKU: 97045001773

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HLA Class I Polyclonal Antibody, 100ul[BT-AP10062] Thermo Mix The coding region of thisHLA A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon

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Description

The coding region of this gene is intronless

The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain

Important for efficient CD180 cell surface expression

Can act as a coreceptor for HIV-1

and it may also play a role in neuroimmune function

HLA Class I Polyclonal Antibody, 100ul[BT-AP10062] Thermo Mix The coding region of thisHLA A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon

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