c-Abl Rabbit Polyclonal Antibody, 100ul Pathway and Network Analysis |enzyme regulation:Strongly inhibited by TIMP-2|

|enzyme regulation:Strongly inhibited by TIMP-2| TIMP-3 and TIMP-4| while TIMP-1 is less efficient

Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients

This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation

Among its related pathways are Creation of C4 and C2 activators and Regulation of actin dynamics for phagocytic cup formation

but not for neutrophils

c-Abl Rabbit Polyclonal Antibody, 100ul Pathway and Network Analysis |enzyme regulation:Strongly inhibited by TIMP-2|This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is regulated by CDC2 mediated phosphorylation,