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Rb Polyclonal Antibody, 50ul[BT-AP07689] Roller Bottles This receptor appears to bind

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Rb Polyclonal Antibody, 50ul[BT-AP07689] Roller Bottles This receptor appears to bindRB transcriptional corepressor 1 encoded by RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

This receptor appears to bind the majority of beta-chemokine family members

Push the limits of your experiments and gain valuable insights

The ligand of this receptor is macrophage inflammatory protein 3 alpha(MIP-3 alpha)

The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation

An important paralog of this gene is SNRNP200

Rb Polyclonal Antibody, 50ul[BT-AP07689] Roller Bottles This receptor appears to bindRB transcriptional corepressor 1 encoded by RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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