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PKC Theta Polyclonal Antibody, 20ul[BT-AP07222] Inoculating Loops/Needles also known as PUMAG or

SKU: 97197487900

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PKC Theta Polyclonal Antibody, 20ul[BT-AP07222] Inoculating Loops/Needles also known as PUMAG orProtein kinase C (PKC) is a family of serine and threonine specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile

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Description

also known as PUMAG or Puma-g

and a C-terminal extracellular region with four N-glycosylation sites

Positively regulates the beta-catenin pathway (canonical Wnt signaling pathway) and is required for MCC-mediated repression of the beta-catenin pathway (PubMed: 24824780)

This protein binds Rab27 and may be involved in inhibiting dense core vesicle exocytosis

Defect in GIPR thus may contribute to the pathogenesis of diabetes

PKC Theta Polyclonal Antibody, 20ul[BT-AP07222] Inoculating Loops/Needles also known as PUMAG orProtein kinase C (PKC) is a family of serine and threonine specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile

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