MARCH2 Polyclonal Antibody, 100ul Recombinant Protein Voltage-sensitive calcium channels mediate the

Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells

Gene Ontology (GO) annotations related to this gene include transporter activity and transmembrane transporter activity

Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins

Inhibin beta C chain is proteolytically processed to generate a subunit of homodimeric and heterodimeric activin complexes

and is a member of the sodium:neurotransmitter symporter family

MARCH2 Polyclonal Antibody, 100ul Recombinant Protein Voltage-sensitive calcium channels mediate theMARCH2 (membrane associated ring CH type finger 2) is a member of the MARCH family of membrane bound E3 ubiquitin ligases. MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome to trans Golgi network (TGN) trafficking.