IRS2 Polyclonal Antibody, 20ul Custom DNA Oligos Alternative splicing of this gene

Alternative splicing of this gene results in two transcript variants encoding different isoforms

Pseudogenes of this gene are found on chromosome 7

These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein

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hydroxysteroid 11-beta dehydrogenase 1(HSD11B1) Homo sapiens The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone

IRS2 Polyclonal Antibody, 20ul Custom DNA Oligos Alternative splicing of this geneIRS2 (insulin receptor substrate 2) encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of IRS2 is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor associated