Phospho-ATR (S428) Polyclonal Antibody, 100ul Vessels Alternatively spliced transcript variants derived

Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified

The phosphorylation of RAD17 checkpoint clamp loader component is required for the DNA-damage-induced cell cycle G2 arrest

The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation

the diabetic state

Interferon-gamma

Phospho-ATR (S428) Polyclonal Antibody, 100ul Vessels Alternatively spliced transcript variants derivedThe protein encoded by ATR (ATR serine threonine kinase) belongs the PI3 PI4 kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1,