Trk A(Phospho Tyr680/Y681) Polyclonal Antibody, 20ul Shaker&Mixing Growth/differentiation factor 15 encoded by

Growth/differentiation factor 15 encoded by GDF15 belongs to the transforming growth factor-beta (TGF-beta) family

a region that includes a cluster of chemokine receptor genes

Defects in EP300 are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer

potentially participating in the degradation of type II collagen-rich cartilage matrix

The encoded protein is a secreted calcium-binding protein which is found in the cytoplasm

Trk A(Phospho Tyr680/Y681) Polyclonal Antibody, 20ul Shaker&Mixing Growth/differentiation factor 15 encoded byThis gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self mutilating behavior,