Phospho-Akt (S473) mouse Monoclonal Antibody(6F8), 50ul Diagnostic Probes & Oligos RAD50 double strand break repair

RAD50 double strand break repair protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends

It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths

Belongs to the tomoregulin family

The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver

The recombination activating gene 1 component is thought to contain most of the catalytic activity

Phospho-Akt (S473) mouse Monoclonal Antibody(6F8), 50ul Diagnostic Probes & Oligos RAD50 double strand break repairThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a