FoxO1(Phospho Ser256) Polyclonal Antibody, 50ul Bio-Reaction Tube Protein numb homolog encoded by

Protein numb homolog encoded by NUMB plays a role in the determination of cell fates during development

The encoded protein plays a role in the early secretory pathway as a heterodimer with zinc transporter 6| and may also regulate zinc sequestration into secretory granules of pancreatic beta cells

Alternatively splicing results in multiple transcript variants

histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer

The protein encoded by this gene is a component of the exocyst complex| a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane

FoxO1(Phospho Ser256) Polyclonal Antibody, 50ul Bio-Reaction Tube Protein numb homolog encoded byThis gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.