Phospho-AIRE-1 (S156) Polyclonal Antibody, 50ul Live Cell Imaging subunit:Interacts with CDC42

subunit:Interacts with CDC42

lung morphogenesis

This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family

The mature protein begins at amino acid 48 and has a 546 aa extracellular domain

ductal carcinoma of the pancreas and colorectal carcinoma

Phospho-AIRE-1 (S156) Polyclonal Antibody, 50ul Live Cell Imaging subunit:Interacts with CDC42AIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and