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NHERF-2 Polyclonal Antibody, 50ul Primary Antibodies Amplification and/or overexpression of ERBB2

SKU: 99894572077

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DKK162.00 DKK186.00

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NHERF-2 Polyclonal Antibody, 50ul Primary Antibodies Amplification and/or overexpression of ERBB2SLC9A3R2 (SLC9A3 regulator 2) encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium hydrogen exchanger 3, and may also regulate the cystic fibrosis

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Description

Amplification and/or overexpression of ERBB2 has been reported in numerous cancers

Because Hedgehog signaling is frequently activated in certain kinds of gastrointestinal cancers

both of which are composed of five homologous subunits forming a transmembrane aqueous pore

The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain

aorta) encoded by ACTA2 belongs to the actin family of proteins

NHERF-2 Polyclonal Antibody, 50ul Primary Antibodies Amplification and/or overexpression of ERBB2SLC9A3R2 (SLC9A3 regulator 2) encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium hydrogen exchanger 3, and may also regulate the cystic fibrosis

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