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IGFBP3 Polyclonal Antibody, 50ul[BT-AP04389] Drug Development and Evaluation The expression of this gene

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IGFBP3 Polyclonal Antibody, 50ul[BT-AP04389] Drug Development and Evaluation The expression of this geneIGFBP3 is a member of the insulin like growth factor binding protein (IGFBP) family and encodes Insulin like growth factor binding protein 3 with an IGFBP domain and a thyroglobulin type I domain. The protein forms a ternary complex with insulin like growth factor acid labile subunit (IGFALS) and either insulin like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half life of IGFs and altering their interaction

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Description

The expression of this gene or the DUOX1 gene is not suppressed by thyroglobulin (Tg)| a macromolecular precursor in thyroid hormone synthesis| while the expression of the DUOX2 and DUOXA2 are significantly suppressed by the Tg

Several transcript variants encoding many different isoforms have been found for EDA

This region is duplicated elsewhere in the human genome

B lymphocyte chemoattractant

Mutations in NME1 have been identified in aggressive neuroblastomas

IGFBP3 Polyclonal Antibody, 50ul[BT-AP04389] Drug Development and Evaluation The expression of this geneIGFBP3 is a member of the insulin like growth factor binding protein (IGFBP) family and encodes Insulin like growth factor binding protein 3 with an IGFBP domain and a thyroglobulin type I domain. The protein forms a ternary complex with insulin like growth factor acid labile subunit (IGFALS) and either insulin like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half life of IGFs and altering their interaction

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