Triapine - CAS# 143621-35-6 0264 a class III HDAC inhibitor

a class III HDAC inhibitor

(2007) Nat Biotech 25: 681-686

A very useful small molecule collection to improve CRISPR editing efficacy

30 μM)-induced protective effects on fibroblasts[2]

Smiles: COC1=CC2=NC=NC(NC3=CC=CC(=C3)C#C)=C2C=C1OCCCCCCC(=O)NO

Triapine - CAS# 143621-35-6 0264 a class III HDAC inhibitorTriapine, also known as 3 AP and OCX 191, CAS No. 143621 35 6, is a synthetic heterocyclic carboxaldehyde thiosemicarbazone with potential antineoplastic activity. Triapine inhibits the enzyme ribonucleotide reductase, resulting in the inhibition of the conversion of ribonucleoside diphosphates to deoxyribonucleotides necessary for DNA synthesis. This agent has been shown to inhibit tumor growth in vitro. Product information CAS Number: 143621 35 6