Y-27632 - Rock Inhibitor. CAS# 146986-50-7 60174 SHP099 was used at 10

SHP099 was used at 10 µM in vitro and cellular assays

Y-27632 was orally dosed at 30 mg/kg to significantly decrease blood pressure

283 and >400 μM respectively)

Smiles: CN1C=C(C=N1)C1C=NN2C(N)=C(Br)C(=NC2=1)[C@@H]1CNCCC1

hypnotic sedative

Y-27632 - Rock Inhibitor. CAS# 146986-50-7 60174 SHP099 was used at 10Y 27632, CAS No. 146986 50 7, is a widely used, selective inhibitor of the Rho associated protein kinase p160ROCK with a Ki value at ~ 0. 14 M. In many studies, it was shown and used to enhance the survival and cloning efficiency of many primary cell types after single cell dissociation without affecting their self renewal properties, including hESC iPSCs, neural stem cells, intestinal stem cells, and mammary epithelial cells. Product information CAS