Icaritin Size:Solid 10 mg InChi: InChI=1S/C13H14ClN3O4/c1-7-4-12(17-21-7)16-13(18)15-9-5-8(14)10(19-2)6-11(9)20-3/h4-6H

InChi: InChI=1S/C13H14ClN3O4/c1-7-4-12(17-21-7)16-13(18)15-9-5-8(14)10(19-2)6-11(9)20-3/h4-6H

Kawamura K

InChiKey: LXFKEVQQSKQXPR-UHFFFAOYSA-N

ClH/c18-12-10-25(11-4-7-19-8-5-11)24-15(12)17(26)22-14-9-21-23-16(14)13-3-1-2-6-20-13

as a therapeutic modality using eight UC cell lines

Icaritin Size:Solid 10 mg InChi: InChI=1S/C13H14ClN3O4/c1-7-4-12(17-21-7)16-13(18)15-9-5-8(14)10(19-2)6-11(9)20-3/h4-6HIcaritin is an oral traditional Chinese medicine, derived from barrenwort, which targets the estrogen receptor 36. IC50 values for Icaritin are 8,13 and 18 M for K562, CML CP and CML BC cells respectively. Icaritin inhibits the invasion and epithelial to mesenchymal transition of glioblastoma cells by targeting EMMPRIN via PTEN AKt HIF 1 signalling. Icaritin suppresses hepatocellular carcinoma initiation and malignant growth through the IL 6 Jak2