Lovastatin Size:Solid 2 mg KU-0059436

KU-0059436

Formula: C6H10N2O3

2 µM concentration in cellular assays to investigate its effects on the PI3K/AKT signaling pathways

InChi: InChI=1S/C12H15N

25)26)9-13-21(18)16(23)8-7-12-20-10-5-4-6-11-20/h7-8

Lovastatin Size:Solid 2 mg KU-0059436Lovastatin inhibits HMGCR, blocking the enzyme catalyzed transformation of 3 hydroxy 3 methylglutaryl CoA into mevalonate. Lovastatin is a statin natural product isolated from numerous sources including the Pleurotus ostreatus oyster mushroom, demonstrating hypocholesterolemic and antiproliferative properties. The biosynthesis of cholesterol requires mevalonate as a building block and elimination of mevalonate generation subsequently interrupts