GSK2334470 - CAS# 1227911-45-6 one (dimaleate) MS-209 restored chemosensitivity of SBC-3

MS-209 restored chemosensitivity of SBC-3 / ADM cells to VP-16

3transCaffeoylquinic acid

RPE cells differentiate into a functional monolayer

Formula: C9H14ClNO2

Chemical Name: (E)-N-methyl-4-(pyridin-3-yl)but-3-en-1-amine hemioxalate

GSK2334470 - CAS# 1227911-45-6 one (dimaleate) MS-209 restored chemosensitivity of SBC-3GSK2334470 is a potent 3 phosphoinositide dependent protein kinase (PDK1) inhibitor (IC50 ~ 10 nM), which does not suppress the activity of 93 other protein kinases including 13 AGC kinases most related to PDK1 at 500 fold higher concentrations. GSK2334470 also inhibited T loop phosphorylation and activation of Akt. GSK2334470 will be a useful tool for delineating the roles of PDK1 in biological processes. Product information CAS Number: 1227911 45 6