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GSK2256098 - CAS# 1224887-10-8 size:2mg solid 51 μM and 1

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GSK2256098 - CAS# 1224887-10-8 size:2mg solid 51 μM and 1GSK2256098, also known as GTPL7939, CAS No. 1224887 10 8, is a focal adhesion kinase 1 (FAK) inhibitor with potential antiangiogenic and antineoplastic activities. FAK inhibitor GSK2256098 inhibits FAK, which may prevent the integrin mediated activation of several downstream signal transduction pathways, including ERK, JNK MAPK and PI3K Akt, thereby inhibiting tumor cell migration, proliferation and survival, and tumor angiogenesis. The tyrosine

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Description

51 μM and 1

is a potent and selective inhibitor of cathepsin K

MK-8776 S-isomer induces accumulation of γ-H2AX within 2 hours

(2014) ACS Chem Biol

SCH900776 S-isomer

GSK2256098 - CAS# 1224887-10-8 size:2mg solid 51 μM and 1GSK2256098, also known as GTPL7939, CAS No. 1224887 10 8, is a focal adhesion kinase 1 (FAK) inhibitor with potential antiangiogenic and antineoplastic activities. FAK inhibitor GSK2256098 inhibits FAK, which may prevent the integrin mediated activation of several downstream signal transduction pathways, including ERK, JNK MAPK and PI3K Akt, thereby inhibiting tumor cell migration, proliferation and survival, and tumor angiogenesis. The tyrosine

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